Welcome to Cross-Canada Paediatric - Respiratory Residency Rounds
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PATHOLOGY

MICROSCOPIC
low and high magnifications


1 lymphoma HE low magnification
ENLARGE

– H/E coloration
– Accumulation of cells like a mass along vessels within normal lung parenchyma.
– Smaller accumulation of cells as a micronodule.


2 lymphoma HE mid magnification
ENLARGE

– Surprisingly, there is no cellular accumulation in the air ways.


3 lymphpma HE high magnification
ENLARGE

– The infiltrate is composed by large lymphoid cells

IMMUNOHISTOCHEMICAL TECHNIQUES


ENLARGE
– Demonstrated a strong positive staining for the CD30


ENLARGE
and EMA antigens

CYTOGENETICAL ANALYSIS
– 2.5 translocation

WOULD ANYONE CARE TO OFFER A FINAL DIAGNOSIS ?


 


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